You might have participated in a debate that involved comparing RAD 140 VS MK 677, but it involved personal opinions that users had about these compounds. However, if you are thinking about adjusting your regime and adding one of these substances to your nutrition, how about consulting science?
We did the footwork for you and analyzed scientific evidence and resources regarding RAD 140 and MK 677. Here are the crucial details about both substances!
What Is RAD 140?
RAD 140 is the developmental name of a compound that actually doesn’t have a common name, and is only known under this abbreviation. It belongs to SARMs – selective androgen receptor modulators. The purpose of these compounds is to have a more selective action than androgenic drugs despite having similar activity.
The jury is still out when it comes to the safety of RAD 140 in treating various conditions. Some indications exist that this compound could help to deal with osteoporosis and muscle wasting in patients dealing with breast cancer. However, it seems that additional trials will have to clear up the confusion that exists around this compound.
Let’s take a look at the currently available scientific evidence regarding RAD 140’s potential benefits.
Research Study 1 – Neuroprotective Properties of RAD 140
A study published in 2014 in Endocrinology focused on male rats and investigating the capability of RAD 140 to provide neuroprotection.  The idea was to see is this compound could have the expected activity to protect and help the user resist neurodegenerative conditions, such as Alzheimer’s.
RAD 140 belongs to selective androgen receptor modulators who interact only with selected tissues. The researchers focused on seeing whether this compound could replace testosterone and have similar effects to that hormone when it comes to decreasing cell death in the brain.
The conclusion was that RAD 140 has neuroprotective properties. The authors indicate it could be helpful for those who are at risk of developing neurodegenerative diseases.
Research Study 2 – Mechanism of Action in Breast Cancers
Several studies focused on the potential effectiveness of RAD 140 in helping to treat symptoms related to breast cancer, including muscle wasting and osteoporosis. A study published in 2017 reveals details on the working process of this SARM in breast cancer. 
The authors indicate that the androgen receptor was detected in up to 95% of estrogen receptor-positive tumors in patients dealing with breast cancer. They suggest the treatment with SARMs makes sense because of this quantity of ARs noted.
The researchers indicate that RAD 140 has anabolic properties for the bones and muscles and helps to prevent muscle wasting. However, it is a potent agonist of the androgen receptors, which is why it can have anti-tumor properties, too.
What Is MK 677?
MK 677 is a different compound than RAD 140. It is a growth hormone secretagogue, which means that it is capable of boosting GH production in the human body. MK 677 does this by mimicking ghrelin and binding to its receptors.
The important characteristic of ibutamoren, which is another name for this compound, is that it is usually safe and comes without adverse side effects. However, staying within the recommended ranges and finding an optimal dose is essential for every user.
The benefits of MK 677 could compare to the ones delivered by the actual growth hormone. Here is an overview of the research available for this substance.
Research Study 1 – Cognitive Function in Healthy Older Men
Before we focus on how MK 677 and the growth hormone affect body composition, let’s talk about the potential of GH and IGF-1 to support optimal cognitive function. According to a study from 1999, IGF-1 (insulin-like growth factor) and the growth hormone are essential for cognitive health in older men. 
The researchers conducted multiple tests, including vocabulary, reading ability, long-term memory, perceptual-motor speed, and others to determine the results of the study. The conclusion was that the higher levels of IGF-1 contributed to better mental performance in healthy older men.
Since ibutamoren is capable of boosting the production of both GH and IGF-1, this compound can also have neuroprotective properties and support optimal cognitive performance.
Research Study 2 – Body Composition and MK 677
Whether you are heading on vacation or are a professional bodybuilder, the dreams of having an ideal body shape are identical. MK 677 is a compound that can help to optimize body composition. The results of a study published in 2008 support that claim. 
The researchers took two years to conduct a trial on 65 participants that were at least 60 years old. They divided the users into two groups, and the first one received a placebo, while the other consumed 25 milligrams of ibutamoren daily.
The results showed that MK 677 boosted the levels of both IGF-1 and GH while remaining safe for its users. The authors indicate that long-term use is well-tolerated, while this compound is capable of helping to achieve the desired body composition. The measurements showed that the participants increased the levels of lean body mass without significant changes in fat levels in their bodies. That can be beneficial for both fitness enthusiasts and professionals. It also shows that MK 677 can be suitable for those looking to get rid of extra pounds and excessive fats while getting lean body mass.
RAD 140 VS MK 677 – Which Is Better for You?
RAD 140 is a selective androgen receptor modulator, which are compounds with specific interaction with these modulators. The idea of this substance is to assist in treating muscle wasting and osteoporosis, especially in those dealing with breast cancer. RAD 140 might even protect the brain cells from neurodegenerative conditions. Unfortunately, not a lot of trials are available, which is why it might be wise to wait for additional research.
Unlike that, MK 677 is a compound that has been confirmed to act as a growth hormone secretagogue. Multiple studies prove that this compound has similar benefits to GH since it increases its production. That means ibutamoren can help you to re-shape your body, boost fat-free mass while accelerating recovery after training.
MK 677 is widely available and used by both fitness enthusiasts, athletes, and other users. Ever since AgeForce designed the skin patch formula containing ibutamoren, this compound’s popularity increased even more.
AgeForce designed the easiest way to use MK 677 when they released the unique skin patches to the market.
The unique skin patch takes only a couple of seconds to apply and change. It features a timed release to secure a steady flow into the bloodstream and optimal absorption. Users find it better than injections and tablets because the application is simple and pain-free.