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MK 677 VS MK 2866 – Ibutamoren and Enobosarm Compared

Although they have similar names, the truth is that MK 677 and MK 2866 are different compounds. It is easy for someone to get them confused because similar names, which is why we will be comparing them in this article. You will discover everything about the potential benefits of both, which should help you make the right choice. Here is a detailed comparison of MK 677 VS MK 2866!

What Is MK 677?

MK677 Molecule

MK 677 is a growth hormone secretagogue, and this compound is famous for mimicking the behavior of the ghrelin hormone. This substance binds to ghrelin receptors to support the production of the growth hormone in the human body.

You will find MK 677 under other names, and the most common one is ibutamoren. It is a safe compound, and it should be well-tolerated as long as used within the recommended ranges. Let’s take a look at what the science has to say regarding the benefits of MK-677.

Research Study 1 – Dealing with Obesity with MK 677

An interesting study was published in Sweden in 1998. [1] It focused on obese men that were between 18 and 50 years old and the effect that ibutamoren treatment might have on obesity. The researchers divided 24 participants into two groups and administered either placebo or 25 milligrams of ibutamoren for eight weeks.

The conclusion was that the basal metabolic rate was significantly increased in the group who received MK 677 therapy. That means those participants accelerated the rate of body fat loss, and they also have a noticeable increase in lean body mass.

Research Study 2 – MK 677 for Accelerating Fracture Healing and Injury Recovery

The growth hormone is capable of speeding up the injury recovery process, and ibutamoren is capable of boosting its production. A study published in 2011 focused on patients that broke their hips and were going through recovery. [2]

The researchers gathered 123 participants who all belonged to an elderly group. They divided them into a group that received 25 milligrams per da of MK 677 and the placebo group. The study lasted for 24 weeks, and the results were encouraging.

The authors noted that a smaller number of patients had problems with falls during the study. The gait speed and the mean stair-climbing power were increased in patients who received MK 677, which are both indicators of accelerated recovery.

Research Study 3 – MK 677 Prevents Diet-Induced Protein Catabolism

It is not easy to shed extra pounds while maintaining muscles and lean body mass. If you are dealing with catabolism induced by diet, MK 677 could help to boost GH production and reverse the process. Those were the results of a study performed in 1999 in the United States. [3]

The researchers gathered eight volunteers who went through a restricted caloric intake for two weeks. They received a placebo or MK 677, and the results showed considerably smaller nitrogen losses when using ibutamoren.

What Is MK 2866?

MK 2866 Molecule

MK 2866 belongs to the group of the so-called SARMS – selective androgen receptor modulators. These compounds are strong and need to be used cautiously. In 2017, the FDA warned users against adding SARMs to their bodybuilding regime. [4]

Apart from MK2866, you can also notice that professionals use names ostarine and enobosarm for this company. Not a lot of information is available on the working process of this compound, but there are several studies discussing their benefits.

Research Study 1 – Using MK 2866 for Cachexia

Cachexia is a syndrome that often appears hand in hand with an underlying medical problem. It causes muscle wasting and loss that is hard to compensate with optimal nutrition. A research study published in 2014 focused on the potential connection of enobosarm and cachexia. [5]

According to the conclusion of this study, MK 2866 is capable of increasing lean body mass and specific measures of power and function. The authors also noticed that the medication was well-tolerated.

Research Study 2 – Another Research Focused on Enobosarm and Muscle Wasting

A study published in The Lancet Oncology in 2013 focused on the effectiveness of enobosarm on muscle wasting in patients that were diagnosed with cancer. [6] The researchers argue that cancer could cause muscle wasting early after the appearance of the disease. They gathered 100 participants of both sexes that are either going through post-menopause or have over 45 years.

The authors divided the participants into three groups. The first group received placebo treatment and the other two MK 2866 in doses of 1mg or 3mg.

The conclusion was that both groups who received enobosarm saw a significant increase in body mass and prevention of muscle wasting.

Research Study 3 – MK 2866 for Accelerating Bone Healing

Calcified Tissue International published a study in 2019 to discuss the effects of ostarine on speeding up the bone healing process in rats. [7] The researchers used ovariectomized animals and the placebo group. They created an osteotomy of the tibia metaphysis and applied treatment of enobosarm in different doses (from 0.04 to 4 milligrams per kilogram).

The conclusion was that an increased dose of MK 2866 could play a beneficial role in accelerating the recovery from bone injuries. The authors indicate that this compound might be dose-dependant, which is why it is essential to find the right dose.

MK 677 VS MK 2866 – Which Is Better for You?

You might think that MK 677 and MK 2866 belong to the same category of compounds, but that is not true. The difference is that MK 2866 is a modulator of androgen receptors, while MK 677 is a growth hormone secretagogue. The former belongs to SARMs and is focused on preventing muscle wasting that might be caused by cachexia.

MK 677 boosts the growth hormone production in the human organism, which secures a long-range of potential benefits. That includes burning excess fat, as well as boosting muscle growth and shortening injury recovery time.

If you would like to try ibutamoren, consider the unique MK 677 skin patches developed by AgeForce. These products are incredibly easy to use since all you need to do is to apply them to your skin, which only takes a couple of seconds.

Buy Ageforce MK677 Patches Here

The gradual transdermal release should secure improved absorption of ibutamoren. Thanks to these patches, you can experience the potential benefits of MK 677 while using a user-friendly application method!

References

  1. https://pubmed.ncbi.nlm.nih.gov/9467542/
  2. https://pubmed.ncbi.nlm.nih.gov/21067829/
  3. https://pubmed.ncbi.nlm.nih.gov/9467534/
  4. https://www.fda.gov/news-events/fda-brief/fda-brief-fda-warns-against-using-sarms-body-building-products
  5. https://www.futuremedicine.com/doi/full/10.2217/fon.13.273
  6. https://www.sciencedirect.com/science/article/abs/pii/S147020451370055X
  7. https://link.springer.com/article/10.1007/s00223-019-00613-1
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