Are you having problems understanding the difference between HGH and IGF-1? Both hormones focus on promoting growth, which is why bodybuilders and fitness enthusiasts love them. Although they share some similarities, these compounds also have certain differences.
In this article, we are conducting a detailed IGF-1 VS HGH comparison. Take a look at the information we gathered to make an informed decision on which of these substances is a better fit for you.
What Is IGF-1?
IGF-1 is an abbreviation for the insulin-like growth factor. The hormone is important for humans of all ages. For children, it takes a critical part in securing optimal growth and development. For adults, the focus is on this compound’s anabolic properties.
It is the liver that mainly produces this hormone. The crucial thing to note is that the human growth hormone promotes the production of IGF-1, which means these two substances are closely related.
IGF-1 should be at its highest levels during puberty and then decrease over time. Medical professionals might resort to prescribing IGF-1 for children dealing with the deficiency of this hormone. What about the scientific research regarding its effects on boosting muscle mass and other benefits for adults? Here is an overview of the evidence we found.
Research Study 1 – IGF-1 Is Crucial for Maintaining Bone Mass
A study published in Nature Medicine in 2012 pinpoints that IGF-1 is the critical bone matrix growth factor.  Its task is to maintain optimal bone mass in adults. The study explains the mechanism of action and details how IGF-1 can boost bone formation.
The authors also explain that patients dealing with osteoporosis might have 40% lower levels of IGF-1 than those who don’t deal with this condition.
Research Study 2 – the Role of IGF-1 in Muscle Regeneration
Trends in Immunology published a study that focused on the role of IGF-1 on muscle regeneration.  According to this article, IGF-1 participates in recruiting cells to the muscle that needs regeneration.
The authors indicate that this hormone can play a role in the inflammatory response once an injury to the muscles occurs.
Research Study 3 – Can IGF-1 Improve Resistance to Oxidative Stress?
A study from 2002 focused on assessing how IGF-1 can affect oxidative stress resistance in mice.  Although the research was animal-based, the results were encouraging.
The authors concluded that IGF-1 is among the hormones that can improve resistance to oxidative stress. Since oxidative stress is among the reasons for aging and cell deterioration, this indicates that IGF-1 can promote a longer lifespan.
What Is HGH?
HGH is the variation of the growth hormone produced by the human organism. The pituitary gland is the place where the body produces this hormone. HGH plays an important role in childhood development, but its levels decrease as we age.
Since the growth hormone is important for muscle growth and other benefits, adults might look for ways of promoting HGH production. Here is what science has to say about this hormone.
Research Study 1 – Dealing with the Growth Hormone Deficiency
The main reason why the doctors prescribe HGH treatment is to deal with the deficiency of this hormone. According to a study from 1999, scientific evidence supports this treatment. 
The researchers focused on administering GH injections and considered whether it would increase quadriceps mass. A total of 28 adults took part in the study, and the results were encouraging. If adults had problems with low levels of the growth hormone, HGH treatment was able to boost their muscle mass.
Research Study 2 – Can HGH Help in Healing Fractures?
You can find multiple studies that show the human growth hormone can play a role in shortening the recovery process after an injury. Those injuries could include burns and other wounds, muscle problems, but also fractures. According to a study from 2009, the human growth hormone was capable of promoting fracture healing in rats. 
The researchers analyzed animals who dealt with fractures in the study that lasted 40 days. The administered doses of the growth hormone varied from none to ten milligrams per kilogram. The authors concluded that the load sustained increased in rats who received the GH treatment. They also confirmed the treatment’s success might vary from the dose administered.
Research Study 3 – Healthy Adults and HGH Treatment
The study from 1988 was unique because it focused on healthy and young adults who were in optimal condition.  The researchers wanted to determine if it is possible to boost lean body mass with the human growth hormone.
The results confirmed what they assumed at the beginning of the study. After six weeks of treatment, the participants increased lean mass while lowering excess fat levels. It is worth noting that an adequate diet also played a role in achieving this goal. That proves optimal nutrition can boost the results of HGH.
Research Study 4 – Elderly Males and the Human Growth Hormones
In 1991, the researchers conducted a study that focused on older adults.  The authors gathered 45 participants that crossed the age of 60, and they were administered GH for 18 months.
The results were impressive – the human growth hormone provided a total increase of muscle areas by 11% while increasing fat-free body mass by 6%. The authors also noted that the participants returned to baseline levels three months after the treatment. It is another confirmation that HGH is directly related to muscle and lean body mass growth.
IGF-1 VS HGH – Which Is Better for You?
The truth is that IGF-1 and HGH can both play a crucial role in benefits that involve promoting cell growth and regeneration. IGF-1 can help to maintain bone mass and improving muscle regeneration, as well as assisting cells in dealing with oxidative stress. As for the HGH, it can serve for treating the deficiency of this hormone, shortening recovery, and achieving fitness goals at a faster rate.
Although HGH might be more common among fitness enthusiasts, both compounds can contribute to achieving the desired body shape and muscle mass. While choosing the desired addition to your fitness regime, make sure to consider the application method. Why would you go through the hassle of using injections when there is an easier alternative?
AgeForce released skin patches with various formulas, and some of them include HGH or IGF-1. Skin patches have a timed-release, which secures a steady flow of compounds and their improved absorption. Applying a patch to your skin is pain-free and incredibly simple.
Skin patches have a timed-release, which secures a steady flow of compounds and their improved absorption. Applying a patch to your skin is pain-free and incredibly simple.