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MelatoninMelatonin with GABA

 

Customer Reviews - We do not monitor or control the content of reviews but reserve the right to remove what are, in our sole opinion, clearly false statements, spam or other injurious materials that are brought to our attention. We do not adopt or endorse any review statement.
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1 of 1 people found the following review helpful
Keeps getting better!
I left a comment over a year ago and the results keep getting better! The sleep is still amazing without feeling tired the next morning. The consistent use of this patch has allowed me to remove an anxiety/sleep medication from my life. My wife has been using it in the same manner with the same results. We couldn't be happier with this patch and the fact I was able to stop taking a poisonous pharmaceutical is a great bonus! Better than any melatonin pill I have ever used! A+
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0 of 1 people found the following review helpful
Wonderful !!!!
I have been directed by many Drs to try melatonin but all oral ones gave me a stomach ache.
This patch has been a Godsend as it delivers it direct into the bloodstream.
I put it on about 1 hour before bed. It does help me sleep better!
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0 of 0 people found the following review helpful
Melatonin.4.deep.sleep!
Have used melatonin for YEARS and it is a great help with calming and settling me down for a much needed good night sleep
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0 of 0 people found the following review helpful
Works great
These patches help you ease into sleep and doesn't leave you with a drugged groggy feeling. Since good sleep is essential to maintaining good health I highly recommend, even if you think you are getting decent sleep you will find with these patches the quality of your sleep is much better.
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1 of 1 people found the following review helpful
Sleep like a baby
I have used many Melatonin products in the past but none works as well as these patches.  I found out the hard way when I ran out for a couple of days.  I fall asleep easily and stay asleep longer, plus so easy to use!  Keep them by my bed and put one on each night and sleep like a baby!
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0 of 0 people found the following review helpful
dreams a plenty
This patch works, it sets a deep sleep cycle when used as instructed. My only mistake was to leave it on and went to work and half way during the morning I was yawning and feeling very calm, I remembered the patch and took it off and  in a short amount of time with coffee was back to normal.
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0 of 0 people found the following review helpful
Melatonin Patches
My wife and myself have been using the Melatonin patches for several years now and they provide and restful and dream filled night's rest.  We both have experienced no signs of grogginess the next morning and we both highly recommend these phenomenal patches!
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1 of 1 people found the following review helpful
Great sleep!
Great sleep without grogginess the next morning!
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References:

Antunes, L. C., et al. "Obesity and shift work: chronobiological aspects." Nutrition research reviews 23.01 (2010): 155-168.)

Arangino, Serenella, et al. "Effects of melatonin on vascular reactivity, catecholamine levels, and blood pressure in healthy men." The American journal of cardiology 83.9 (1999): 1417-1419.

Arendt, Josephine, and James Broadway. "Light and melatonin as zeitgebers in man." Chronobiology international 4.2 (1987): 273-282.

Blask, David E., et al. "Oral melatonin supplementation in rats and a human subject suppresses the growth activity of steroid receptor negative human breast cancer xenografts in female nude rats via an MT1 receptor-mediated suppression of signal tranduction and linoleic acid uptake and metabolism." Proceedings of the American Association for Cancer Research 2005.1 (2005): 1358.

Bonnefont-Rousselot, Dominique. "Obesity and Oxidative Stress: Potential Roles of Melatonin as Antioxidant and Metabolic Regulator." Endocrine, metabolic & immune disorders drug targets (2014).

Bray, M. S., and M. E. Young. "Circadian rhythms in the development of obesity: potential role for the circadian clock within the adipocyte." obesity reviews 8.2 (2007): 169-181.

Cagnacci, Angelo, et al. "Influences of melatonin administration on the circulation of women." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 274.2 (1998): R335-R338.

Cagnacci, Angelo, et al. "Influence of melatonin administration on glucose tolerance and insulin sensitivity of postmenopausal women." Clinical endocrinology 54.3 (2001): 339-346.

CipollaNeto, J., et al. "Melatonin, energy metabolism, and obesity: a review." Journal of pineal research 56.4 (2014): 371-381.

Hansen, Johnni. "Increased breast cancer risk among women who work predominantly at night." Epidemiology 12.1 (2001): 74-77.

Karasek, M. "Melatonin, human aging, and age-related diseases." Experimental gerontology 39.11 (2004): 1723-1729.

Kędziora‐Kornatowska, Kornelia, et al. "Effect of melatonin on the oxidative stress in erythrocytes of healthy young and elderly subjects*." Journal of pineal research 42.2 (2007): 153-158.

Kędziora‐Kornatowska, Kornelia, et al. "Antioxidative effects of melatonin administration in elderly primary essential hypertension patients." Journal of pineal research 45.3 (2008): 312-317.

Kędziora‐Kornatowska, Kornelia, et al. "Melatonin improves oxidative stress parameters measured in the blood of elderly type 2 diabetic patients." Journal of pineal research 46.3 (2009): 333-337.

Koziróg, Marzena, et al. "Melatonin treatment improves blood pressure, lipid profile, and parameters of oxidative stress in patients with metabolic syndrome." Journal of pineal research 50.3 (2011): 261-266.

Kubo, Tatsuhiko, et al. "Prospective cohort study of the risk of prostate cancer among rotating-shift workers: findings from the Japan collaborative cohort study." American Journal of Epidemiology 164.6 (2006): 549-555.

Nduhirabandi, Frederic, Eugene F. du Toit, and Amanda Lochner. "Melatonin and the metabolic syndrome: a tool for effective therapy in obesityassociated abnormalities?." Acta physiologica 205.2 (2012): 209-223.

Peng, Cai-Xia, et al. "Disease-modified glycogen synthase kinase-3β intervention by melatonin arrests the pathology and memory deficits in an Alzheimer's animal model." Neurobiology of aging 34.6 (2013): 1555-1563.

Polimeni, Giovanni, et al. "Role of melatonin supplementation in neurodegenerative disorders." Frontiers in bioscience (Landmark edition) 19 (2013): 429-446.

Prunet-Marcassus, Benedicte, et al. "Melatonin reduces body weight gain in Sprague Dawley rats with diet-induced obesity." Endocrinology 144.12 (2003): 5347-5352.

Ramírez-Rodríguez, Gerardo, et al. "Melatonin supplementation delays the decline of adult hippocampal neurogenesis during normal aging of mice." Neuroscience letters 530.1 (2012): 53-58.

Ray, Chester A. "Melatonin attenuates the sympathetic nerve responses to orthostatic stress in humans." The Journal of physiology 551.3 (2003): 1043-1048.

Reiter, Russel J., et al. "Obesity and metabolic syndrome: association with chronodisruption, sleep deprivation, and melatonin suppression." Annals of medicine 44.6 (2012): 564-577.

Sack, Robert L., et al. "Human melatonin production decreases with age." Journal of pineal research 3.4 (1986): 379-388.

Tan, DX., et al. "Significance and application of melatonin in the regulation of brown adipose tissue metabolism: relation to human obesity." Obesity Reviews 12.3 (2011): 167-188.

Terzolo, Massimo, et al. "Effects of LongTerm, LowDose, TimeSpecified Melatonin Administration on Endocrine and Cardiovascular Variables in Adult Men." Journal of pineal research 9.2 (1990): 113-124.

Viswanathan, Akila N., Susan E. Hankinson, and Eva S. Schernhammer. "Night shift work and the risk of endometrial cancer." Cancer Research 67.21 (2007): 10618-10622.

Wu, YingHui, and Dick F. Swaab. "The human pineal gland and melatonin in aging and Alzheimer's disease." Journal of pineal research 38.3 (2005): 145-152.

Yilmaz, Bayram, et al. "Melatonin inhibits testosterone secretion by acting at hypothalamo-pituitary-gonadal axis in the rat." Neuro endocrinology letters 21.4 (2000): 301.

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