Growth Hormone Simulates Healing Of Damaged Tissue

In an article published December-2003, The University Of Chicago published a paper supporting the findings that not only does the administration of growth hormone increase lean body mass and increase bone density, but that it also “activates a gene critical for the body's tissues to heal and regenerate,” says Robert Costa, professor of biochemistry and molecular genetics at the University of Illinois at Chicago and a member of the UIC Cancer Center. This discovery should also help to explain how and we age. "Growth hormone levels decline as we grow older; as a result, the Foxm1b gene stops working and our bodies are less capable of repairing damage," Costa said. In the present study, the scientists tested the effects of human growth hormone because of its purported role in stimulating cell proliferation. Growth hormone, a substance secreted by the pituitary gland in the brain, is responsible for growth in children and young adults, but its levels decline during aging. "The literature had suggested that growth hormone therapy in elderly men stimulates cells to divide," said Costa, leading to increases in muscle mass and skin thickness and greater bone density in the spine, while decreasing body fat.

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